The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 13, 2001
Filed:
Nov. 06, 2000
Applicant:
Inventors:
Jean-Marie Lehn, Strasbourg, FR;
Pierre Lehn, Paris, FR;
Jean-Pierre Vigneron, Boissy-sur-Saint-Yon, FR;
Assignee:
Centre National de la Recherche Scientifique, Paris, FR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 4/304 ; A61K 3/170 ; A61K 9/127 ; C07C 6/974 ; C12N 5/00 ;
U.S. Cl.
CPC ...
A01N 4/304 ; A61K 3/170 ; A61K 9/127 ; C07C 6/974 ; C12N 5/00 ;
Abstract
Novel amidinium derivatives of formula (I), wherein R1 is a cholesterol derivative or an alkylamino-NR′R″ grouping, and each of R2 and R3 is independently a hydrogen atom or a grouping of formula (II), wherein each of R4 and R5 is independently a hydrogen atom or a grouping of formula (III), are disclosed. The corresponding pharmaceutical compositions, which are particularly useful in gene therapy for transferring therapeutic genes into cells, are also disclosed.