The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 13, 2001
Filed:
Apr. 30, 1999
Applicant:
Inventors:
Gerald Crabtree, Woodside, CA (US);
Stuart Schreiber, Boston, MA (US);
David Spencer, Houston, TX (US);
Thomas Wandless, Palo Alto, CA (US);
Peter Belshaw, Somerville, MA (US);
Steffan N Ho, San Diego, CA (US);
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/170 ; A61K 3/812 ; A61K 4/800 ; C12N 5/10 ;
U.S. Cl.
CPC ...
A61K 3/170 ; A61K 3/812 ; A61K 4/800 ; C12N 5/10 ;
Abstract
We have developed a general procedure for the regulated (inducible) dimerization or oligomerization of intracellular proteins and disclose methods and materials for using that procedure to regulatably initiate cell-specific apoptosis (programmed cell death) in genetically engineered cells.