The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 06, 2001

Filed:

Mar. 20, 2000
Applicant:
Inventors:

Ambarish Singh, Bordentown, NJ (US);

Chien-Kuang Chen, Marlboro, NJ (US);

John A. Grosso, Princeton Jct, NJ (US);

Edward J. Delaney, Princeton, NJ (US);

Xuebao Wang, East Brunswick, NJ (US);

Richard P. Polniaszek, Dayton, NJ (US);

John K. Thottathil, Princeton, NJ (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ;
U.S. Cl.
CPC ...
C07D / ; C07D / ;
Abstract

Methods for the preparation of biphenyl isoxazole sulfonamides and intermediates therof. The present invention also relates to the novel intermediates prepared by these methods. The biphenyl isoxazole sulfonamides prepared by the present methods are endothelin antagonists useful, inter alia, for the treatment of hypertension, congestive heart failure and male erectile dysfunction.


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