The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 06, 2001
Filed:
May. 25, 1995
Applicant:
Inventors:
Thomas R. Sykes, Edmonton, Alberta, CA;
Thomas K. Woo, Edmonton, Alberta, CA;
Antoine A. Noujaim, Edmonton, Alberta, CA;
Pei Qi, Edmonton, Alberta, CA;
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/618 ; C07K 1/13 ;
U.S. Cl.
CPC ...
C07K 1/618 ; C07K 1/13 ;
Abstract
A protein containing one or more disulfide bonds, e.g., an antibody, is subjected to ultraviolet radiation to reduce one or more such bonds to reactive sulfhydryl groups; the resulting photoactivated protein is reacted with other chemical entity which is reactive with sulfhydryl, such as certain radiometals, chelating agents, drugs and toxins, so as to obtain a conjugate useful in, e.g., in vitro diagnosis, in vivo imaging, and therapy.