The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 06, 2001

Filed:

Feb. 10, 1997
Applicant:
Inventors:

Michael B. Brenner, Ashland, MA (US);

Jack L. Strominger, Lexington, MA (US);

Johnathan Seidman, Mitlon, MA (US);

Stephen H. Ip, Framingham, MA (US);

Michael S. Krangel, Newtonville, MA (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/800 ;
U.S. Cl.
CPC ...
A61K 3/800 ;
Abstract

The present invention provides purified polypeptides which comprise at least a portion of a &dgr; T cell receptor polypeptide, a &ggr; T cell receptor polypeptide, a &ggr;, &dgr; T cell receptor complex or a &ggr;, &ggr; T cell receptor complex. Substances capable of forming complexes with these polypeptides are also provided. Additionally, methods for detecting T cells which have within them or on their surfaces a polypeptide of the present invention are provided. Moreover, methods for diagnosing immune system abnormalities are provided which comprise measuring in a sample from a subject the number of T cells which have within them or on their surfaces a polypeptide of the present invention.


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