The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 06, 2001

Filed:

Apr. 03, 2000
Applicant:
Inventor:

Gloria Anne Breault, Macclesfield, GB;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/144 ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/144 ; C07D / ; C07D / ;
Abstract

Compounds antagonistic of the pain enhancing effects of prostaglandins are disclosed. The compounds comprise an optionally-substituted A ring with a —CH(R,)N(R,)B—R,and —OD groups positioned in a 1,2 relationship to one another on ring carbon atoms. The 3-position ring-atom is not substituted. B is an optionally-substituted pyridyl ring and the group R,is positioned on B in a 1,3 or 1,4 relationship with the —CH(R,)N(R,)B- linking group. R,, R,and R,and D can be a number of different organic or halogen moieties. N-oxides of —NR,and S-oxides of sulphur containing rings are disclosed as are processes for the preparation of the compounds, intermediates in their preparation, pharmaceutical compositions containing them, and their use as therapeutic agents.


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