The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 06, 2001

Filed:

Oct. 06, 1994
Applicant:
Inventors:

Julian Adams, Ridgefield, CT (US);

Pierre Louis Beaulieu, Montreal, CA;

Robert Déziel, Ville Mont-Royal, CA;

Neil Moss, Laval, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/800 ; C07K 5/00 ; C07K 7/00 ;
U.S. Cl.
CPC ...
A61K 3/800 ; C07K 5/00 ; C07K 7/00 ;
Abstract

Disclosed herein are tetrapeptide derivatives of the formula X—NH—CHR,—C(W,)—NR,—CH[CH,C(O)—Y]—C(W,)—NH—CH[CR,(R,)—COOH]—C(W,)—NH—CHR,—Z wherein X is a terminal group, for example, alkanoyl or phenylalkanoyl radicals, R,and R,are selected from amino acid or derived amino acid residues, R,is hydrogen, alkyl or phenylalkyl, R,and R,are hydrogen or alkyl or R,and R,are joined to form a cycloalkyl, W,, W,and W,are oxo or thioxo, Y is, for example, an alkoxy or a monosubstituted or disubstituted amino, and Z is a terminal unit, for example, hydrogen, COOH or CH,OH. The derivatives are useful for treating herpes infections.


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