The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 06, 2001

Filed:

Apr. 22, 1997
Applicant:
Inventors:

Patrice Yeh, Paris, FR;

Michel Perricaudet, Ecrosnes, FR;

Cécile Orsini, Paris, FR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/5861 ; A61K 4/800 ;
U.S. Cl.
CPC ...
C12N 1/5861 ; A61K 4/800 ;
Abstract

Novel adenovirus-derived viral vectors, the preparation thereof, and their use in gene therapy, are disclosed. In particular, recombinant adenoviruses including an adenovirus genome wherein (i) the E1 region is inactivated, (ii) the genomic organization is modified, and (iii) optional recombination with the producing line genome generates non-viable viral particles, are disclosed.


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