The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 30, 2001
Filed:
Apr. 30, 1999
Martin John Calverley, Herlev, DK;
Henrik Pedersen, Roskilde, DK;
Leo Pharmaceutical Products Ltd., Ballerup, DK;
Abstract
The present invention relates to compounds of formula (I) in which formula X is hydrogen or hydroxy; R,and R,which may be the same or different, stand for hydrogen or C,-C,hydrocarbyl; or R,and R,, taken together with the carbon atom bearing the group X, can form a C,C,carbocyclic ring; Q is methylene, ethylene, tri- or tetra-methylene and may optionally be substituted with an oxy group, —OR,, in which R,is hydrogen, methyl or ethyl; Y is either a single bond or C,-C,hydrocarbylene; and one or more carbons with in R,, R,, and/or Y may optionally be substituted with one or more fluorine atoms, or with a hydroxyl group. The compounds show anti-inflammatory and immunomodulating effects as well as strong activity in inducing differentiation and inhibiting undesirable proliferation of certain cells.