The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 30, 2001
Filed:
Nov. 09, 1999
Applicant:
Inventors:
Osamu Nishimura, Hyogo, JP;
Masato Suenaga, Hyogo, JP;
Hiroaki Ohmae, Nara, JP;
Shinji Tsuji, Hyogo, JP;
Assignee:
Takeda Chemical Industries, Ltd., Osaka, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 2/106 ; C07K 1/107 ;
U.S. Cl.
CPC ...
C12P 2/106 ; C07K 1/107 ;
Abstract
The present invention provides a method for chemically removing a N-terminal methionine residue selectively, specifically and efficiently from a peptide or a salt thereof having an optionally oxidized methinine residue at its N-terminal. The method reacts a peptide or a salt thereof having an optionally oxidized methinine residue at its N-terminal with an &agr;-diketone derivative, followed by hydrolysis.