The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 30, 2001
Filed:
Nov. 24, 1997
William J. Dower, Menlo Park, CA (US);
Christian M. Gates, Santa Cruz, CA (US);
Gregory L. Heinkel, San Jose, CA (US);
Guy Lalonde, Woodside, CA (US);
Larry C. Mattheakis, Cupertino, CA (US);
Christopher J. Paddon, Pacifica, CA (US);
Peter J. Schatz, Mountain View, CA (US);
Glaxo Wellcome Inc., Research Triangle Park, NC (US);
Abstract
The invention provides methods for screening libraries of complexes for compounds having a desired property, especially, the capacity to agonize, bind to, or antagonize a cellular receptor. The complexes in such libraries comprise a compound under test, a tag recording at least one step in synthesis of the compound, and a tether susceptible to modification by a reporter molecule. Modification of the tether is used to signify that a complex contains a compound having a desired property. The tag can be decoded to reveal at least one step in the synthesis of such a compound.