The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 30, 2001
Filed:
May. 13, 1999
Applicant:
Inventors:
Graham Henry Farrar, Salisbury, GB;
Anne Margaret Tinsley-Bown, Salisbury, GB;
David Hugh Jones, Montreal, CA;
Assignee:
Microbiological Research Authority, Salisbury, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01J 1/302 ; B01J 1/304 ; B01J 1/320 ; B05D 7/00 ;
U.S. Cl.
CPC ...
B01J 1/302 ; B01J 1/304 ; B01J 1/320 ; B05D 7/00 ;
Abstract
Bioactive agent is encapsulated in a polymer microparticle in a (water-in-oil)-in-water emulsion-based method, and using a solvent that comprises ethyl acetate. Also described are microparticles comprising low inherent viscosity (i.v.) PLG, some with i.v. less than 0.5dl/g, and methods for their preparation. DNA release is modified through use of low i.v. PLG. A particle production method for scale-up uses a blender that avoids excessive shear damage to DNA being encapsulated.