The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 23, 2001

Filed:

Nov. 21, 1997
Applicant:
Inventors:

David John King, Camberley, GB;

John Robert Adair, High Wycombe, GB;

Raymond John Owens, Henley-on-Thames, GB;

Assignee:

Celltech Limited, Berkshire, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/630 ; C07K 1/628 ;
U.S. Cl.
CPC ...
C07K 1/630 ; C07K 1/628 ;
Abstract

A33 antigen binding proteins are described for use in the diagnosis or treatment of colorectal tumors and metastases arising therefrom. The binding protein may be a humanized A33 antibody, including complete antibody molecules, fragments thereof, and particularly, multivalent monospecific proteins comprising two, three, four or more antibodies or fragments thereof, bound to each other by a cross-linking agent. For diagnosis or therapy, the humanized A33 antibody may be linked to a reporter or effector molecule.


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