The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 23, 2001
Filed:
Aug. 22, 2000
Abstract
Compounds of formula (I), wherein: R,is —CN, —CH(CN)—R,, —CH═C(CN)—R,, —CH,—CH(CN)—R,, —C(═NOH)—NH,, —C(═NH)—NH,, —CH═C(NO,)—R,, —CH(CN)—R,, —CH(CH,NO,)—R,; 5-tetrazolyl, 2-(4,5-dihydrooxazolyl), 1,2,4-oxadiazolin-3-yl-5-one; R,is hydrogen; R,is hydrogen, OR,; R,is hydrogen, C,-C,linear or branched alkyl, CN, COOR,; R,is hydrogen, OR,; R,is hydrogen, C,-C,linear or branched alkyl, (C,-C,) aryl (C,-C,) alkyl, (C,-C,) alkoxy (C,-C,) alkyl, (C,-C,) alkyl (C,-C,) aryl, (C,-C,) aryl (C,-C,) acyl, (C,-C,) acyl, amino (C,-C,) alkyl, amino (C,-C,) acyl, glycosyl; R,is hydrogen, C,-C,linear or branched alkyl, (C,-C,) aryl (C,-C,) alkyl, (C,-C,) alkoxy (C,-C,) alkyl, (C,-C,) alkyl (C,-C,) aryl; R,has the same meanings of R,, independently of the latter. These compounds are active as topoisomerase I inhibitors and can be used as antitumor drugs.