The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 16, 2001

Filed:

Apr. 14, 2000
Applicant:
Inventors:

Jean-Francois Patoiseau, Castres, FR;

Elisabeth Dupont-Passelaigue, Castres, FR;

Wouter Koek, Viviers-les Montagnes, FR;

Assignee:

Pierre Fabre Medicament, Boulogne, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/153 ; A61P 2/518 ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/153 ; A61P 2/518 ; C07D / ;
Abstract

The invention concerns novel 3-oxo-(2H)-1,2,4-triazine derivatives of general formula (I) in which R,represents: hydrogen, when A is an optionally substituted nitrogen atom; a linear or branched,-C,alkyl group; a C,-C,phenyl alkyl group, the phenyl ring being optionally substituted by one or several groups such as C,-C,alkyl, C,-C,alkoxy, halogen, trifluoromethyl. R,represents: hydrogen; a linear or branched C,-C,alkyl radical; a C,phenyl or phenylalkyl group, the phenyl ring being optionally substituted by one or several groups such as C,-C,alkyl, C,-C,alkoxy, halogen, trifluoromethyl. A represents an oxygen atom or a nitrogen atom optionally NR,substituted. R,represents hydrogen or a methyl group. B represents a group such as (IIa) in which Ar itself represents an aromatic structure such as phenyl, pyridyl or pyrimidyl, optionally substituted by one or several groups such as C,-C,alkyl, C,-C,alkoxy, hydroxy, trifluoromethyl or halogen and n can be whole numbers ranging between 3 and 5; (IIb) in which Ar is as defined in formula (IIa) and m can be a whole number ranging between 1 and 2; (IIc) in which R,represents hydrogen or a C,-C,alkyl group and n can be whole numbers ranging between 3 and 5.


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