The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 09, 2001
Filed:
Jun. 05, 1995
Applicant:
Inventors:
John Anthony Hardy, Tampa, FL (US);
Marie-Christine Chartier-Harlin, Villeneuve d'Ascq, FR;
Alison Mary Goate, St. Louis, MO (US);
Michael John Owen, South Glamorgan, GB;
Michael John Mullan, Tampa, FL (US);
Assignee:
Elan Pharmaceuticals, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01K 6/7027 ; A01K 6/7033 ; G01N 3/300 ;
U.S. Cl.
CPC ...
A01K 6/7027 ; A01K 6/7033 ; G01N 3/300 ;
Abstract
Model systems of Alzheimer's disease comprise a DNA sequence encoding an amyloid precursor protein (APP) isoform or fragment that has an amino acid substitution. The substituted amino acid may be other than valine at the amino acid position corresponding to amino acid residue position 717 of APP770. Methods of determining genetic predisposition to Alzheimer's disease are also disclosed.