The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 09, 2001
Filed:
Jun. 28, 1994
Applicant:
Inventors:
Assignee:
Juridical Foundation the Chemo-Sero-Therapeutic Research Institute, Kumamoto-ken, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/509 ; C12P 2/106 ; C12P 2/104 ;
U.S. Cl.
CPC ...
C12N 1/509 ; C12P 2/106 ; C12P 2/104 ;
Abstract
In a process for preparing Tissue Factor Pathway Inhibitor (TFPI) by the genetically engineered technique by the use of a transformed animal cell wherein a DNA encoding human TFPI is introduced, the improvement which comprises culturing said transformed animal cell in a culture medium supplemented with a sulfated polysaccharide to protect an intact TFPI produced by said transformed animal cell from cleavage by proteases present in the culture medium.