The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 09, 2001
Filed:
Jul. 14, 1999
Applicant:
Inventor:
Kenneth Dawson Bagshawe, London, GB;
Assignee:
Enzacta R & D Limited, , GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/9395 ; A61K 3/843 ; C07K 1/628 ; C07K 1/700 ;
U.S. Cl.
CPC ...
A61K 3/9395 ; A61K 3/843 ; C07K 1/628 ; C07K 1/700 ;
Abstract
A compound comprises a target cell-specific portion, such as an antibody specific to tumor cell antigens, and an inactivating portion, such as an enzyme, capable of converting a substance which in its native state is able to inhibit the effect of a cytotoxic agent into a substance which has less effect against said cytotoxic agent. The prolonged action of a cytotoxic agent at tumor sites is therefore possible while protecting normal tissues from the effects of the cytotoxic agent.