The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 02, 2001
Filed:
Jun. 22, 2000
Applicant:
Inventors:
Daniel F. Ortwine, Saline, MI (US);
Claude F. Purchase, Jr., Ann Arbor, MI (US);
Andrew D. White, Lakeland, MI (US);
Assignee:
Warner-Lambert Company, Morris Plains, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/1451 ; A61K 3/1495 ;
U.S. Cl.
CPC ...
A61K 3/1451 ; A61K 3/1495 ;
Abstract
Sulfonamide compounds are described which are inhibitors of matrix metalloproteinases, particularly stromelysin-1 and gelatinase A (72 kD gelatinase). Also described are methods for the treatment of multiple sclerosis, atherosclerotic plaque rupture, aortic aneurism, heart failure, restenosis, periodontal disease, corneal ulceration, burns, decubital ulcers, chronic ulcers or wounds, cancer metastasis, tumor angiogenesis, arthritis, or other autoimmune or inflammatory disorders dependent upon tissue invasion by leukocytes using the compounds.