The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 02, 2001
Filed:
Oct. 06, 1998
Applicant:
Inventors:
S. Jane deSolms, Norristown, PA (US);
John H. Hutchinson, Philadelphia, PA (US);
Anthony W. Shaw, Lansdale, PA (US);
Samuel L. Graham, Schwenksville, PA (US);
Terrence M. Ciccarone, Telford, PA (US);
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/14174 ; A61K 3/15377 ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/14174 ; A61K 3/15377 ; C07D / ; C07D / ;
Abstract
The present invention is directed to compounds which inhibit a prenyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting a prenyl-protein transferase and the prenylation of the oncogene protein Ras.