The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 02, 2001

Filed:

Jul. 31, 1996
Applicant:
Inventor:

Michael E. Spurlock, Pacific, MO (US);

Assignee:

Purina Mills, Inc., St. Louis, MO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/4435 ; C12N 1/21 ; C12N 1/512 ; C12N 1/563 ;
U.S. Cl.
CPC ...
C07K 1/4435 ; C12N 1/21 ; C12N 1/512 ; C12N 1/563 ;
Abstract

A bovine adipocyte-specific polypeptide, termed leptin, is expressed in the fat tissue of cattle. Expression may be altered in over fat cattle, or expression may be in the form of a protein of lesser biological activity relative to that of leaner cattle. The bovine adipocyte polypeptide, DNA and RNA molecules coding therefor, methods for its preparation, and antibodies specific for the polypeptide are disclosed. Methods for determining the susceptibility of cattle to fat deposition are based on measuring the levels of the bovine adipocyte polypeptide in a biological fluid or tissue extract or by measuring mRNA encoding the bovine adipocyte polypeptide in cells of the subject. Methods of evaluating an agent related to the deposition of fat in cattle comprise contacting the agent with an adipocyte in vitro and measuring the amount of the bovine adipocyte polypeptide or mRNA that is produced by the adipocyte. Methods of limiting fat deposition include administering leptin or leptin DNA, and methods of altering intake include administering leptin, leptin DNA, or an antibody directed against leptin.


Find Patent Forward Citations

Spurlock, Michael. (2001). Bovine leptin protein, nucleic acid sequences coding therefor and uses thereof (U.S. Patent No. 6297027). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6297027

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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