The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 25, 2001

Filed:

Dec. 09, 1999
Applicant:
Inventors:

Shingo Yano, Kawagoe, JP;

Yukio Tada, Higashimatsuyama, JP;

Hideki Kazuno, Hanno, JP;

Tsutomu Sato, Hanno, JP;

Junichi Yamashita, Honjo, JP;

Norihiko Suzuki, Hidaka, JP;

Tomohiro Emura, Iruma, JP;

Masakazu Fukushima, Hanno, JP;

Tetsuji Asao, Tokorozawa, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/1535 ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/1535 ; C07D / ; C07D / ; C07D / ;
Abstract

The invention relates to novel uracil derivatives having excellent inhibiting effects on human derived thymidine phosphorylates and anti-tumor activity. The pharmaceutical compositions, anti-tumor potentiators and antitumor agents containing such novel compounds, and a process for their preparation and use are described. The novel uracil derivative compounds are represented by the general formula (1′):


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