The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 18, 2001
Filed:
Jan. 29, 1999
Applicant:
Inventors:
Sanford D. Markowitz, Pepper Pike, OH (US);
Michael G. Brattain, San Antonio, TX (US);
James K. V. Willson, Shaker Heights, OH (US);
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/21 ; C12N 5/10 ; C12N 1/512 ; C12N 1/563 ;
U.S. Cl.
CPC ...
C12N 1/21 ; C12N 5/10 ; C12N 1/512 ; C12N 1/563 ;
Abstract
This invention is based on the discovery that the type II TGF&bgr; receptor (RII) is a cancer suppressor gene which is genetically inactivated (mutated) in approximately 25% of colon cancers, including nearly all colon cancers of the class identified as mutator/microsatellite instability/RER. Methods are provided for detecting inactivation of RII for use in cancer diagnosis or prognosis.
Quick Actions:
Markowitz, Sanford. (2001). Cancer diagnosis and therapy based on mutations in tgf-&bgr; receptors (U.S. Patent No. 6291237). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6291237
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile