The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 18, 2001

Filed:

Nov. 10, 1999
Applicant:
Inventors:

Nicholas J. Schork, Shaker Heights, OH (US);

Laurent Essioux, Paris, FR;

Annick Cohen-Akenine, Paris, FR;

Marta Blumenfeld, Paris, FR;

Daniel Cohen, Neuilly-sur-Seine, FR;

Assignee:

Genset, Paris, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/68 ; G01N 3/100 ;
U.S. Cl.
CPC ...
C12Q 1/68 ; G01N 3/100 ;
Abstract

The present invention relates to methods, software, and apparati for determining whether a genomic region harbors a gene associated with a detectable trait. In one embodiment, the present invention relates to a method of confirming that a genomic region harbors a gene associated with a detectable trait comprising the steps of identifying a candidate genomic region suspected of harboring the gene associated with the detectable trait, constructing a trait-associated distribution of association values using the biallelic markers in the candidate genomic region, identifying a plurality of biallelic markers in random genomic regions which are not suspected of harboring the gene associated with the detectable trait, constructing a random distribution of association values using the biallelic markers in the random genomic regions, comparing the trait-associated distribution of association values to the random distribution of association values, and determining whether the trait-associated distribution of association values and the random distribution of association values are significantly different from one another. In other embodiments, the present invention comprises software for performing the above method and devices comprising the software in a retrievable form.


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