The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 18, 2001
Filed:
Jun. 03, 1998
Applicant:
Inventors:
David B. Volkin, Doylestown, PA (US);
Su-Pi Sheu, Maple Glen, PA (US);
Carl J. Burke, Pennsburg, PA (US);
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/912 ; A61K 3/9165 ; C12N 7/00 ;
U.S. Cl.
CPC ...
A61K 3/912 ; A61K 3/9165 ; C12N 7/00 ;
Abstract
Vaccine stabilizers, vaccine formulations and lyophilized vaccines with enhanced thermostability are disclosed. The vaccine formulations comprise an increased amount of a 6-carbon polyhydric alcohol (such as sorbitol), an increase amount of a disaccharide (such as sucrose) and an amount of a physiologically active buffer to adjust the pH from about 6.0 to about 7.0.