The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 18, 2001

Filed:

Apr. 10, 1996
Applicant:
Inventors:

Klaas Poelstra, Buitenpost, NL;

Machiel Josephus Hardonk, Groningen, NL;

Winston Willem Bakker, Woltersum, NL;

Dirk KLaas Fokke Meijer, Groningen, NL;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/845 ; A61K 3/854 ; A61K 4/800 ; C12N 9/00 ;
U.S. Cl.
CPC ...
A61K 3/845 ; A61K 3/854 ; A61K 4/800 ; C12N 9/00 ;
Abstract

The invention relates to pharmaceutical compositions suitable for treating or curing clinical complications mediated by endotoxin, including sepsis. The compositions contain components suitable for detoxifying endotoxin rendering it less deleterious to mammals such as humans, in particular to patients with reduced host-defence resistance. The invention also relates to pharmaceutical compositions suitable for stimulating bone formation, e.g. for mending broken bone or for prophylaxis or therapy of metabolic bone diseases such as osteoporosis and osteomalacia and pharmaceutical compositions for decreasing or inhibiting undesired bone formation. The pharmaceutical compositions according to the invention are directed at modulating phosphatase activity in vivo.


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