The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 11, 2001
Filed:
Jun. 16, 1999
Sebastianus J. Halkes, Weesp, NL;
Jan Paul Van De Velde, Weesp, NL;
Silvia Kanzler, Weesp, NL;
Wolfgang Reischl, Weesp, NL;
Kingdom of the Netherlands, , NL;
Abstract
The invention relates to vitamin D analogs of general formula (I) wherein: R,is a hydrogen atom or a substituent selected from the group consisting of hydroxy, CH,OH, CH,CH,OH, CH,CH,CH,OH, OCH,, OCH,OH, OCH,CH,OH and OCH,CH,CH,OH; R,is a hydrogen atom or a substituent selected from the group consisting of OCH,, OCH,OH, CH,(CH,OH),(CH,CH,OH),, (CH,),OH and O(CH,),OH; wherein: m is 0 or 1, p, q and n are 0-3, r is 1-3 and m+n+p=3; with the proviso that R,and/or R,contain at least one OH group; R,is a straight or branched, saturated or unsaturated aliphatic hydrocarbon of 6-13 C atoms which may be substituted with one or more substituents from the group hydroxy or fluoro. The invention further relates to methods of preparing these compounds, a pharmaceutical composition containing these compounds and to their use in pharmacotherapy and cosmetics.