The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 11, 2001

Filed:

May. 14, 1997
Applicant:
Inventors:

Magnus Höök, Houston, TX (US);

Joseph M. Patti, Missouri City, TX (US);

Karen House-Pompeo, Valdosta, GA (US);

Narayana Sthanam, Vestavia, AL (US);

Jindrich Symersky, Birmingham, AL (US);

Assignee:

Texas A&M University Systems, College Station, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/600 ; C12P 2/108 ; A61K 3/9395 ; A61K 3/940 ;
U.S. Cl.
CPC ...
C07K 1/600 ; C12P 2/108 ; A61K 3/9395 ; A61K 3/940 ;
Abstract

Disclosed are the cna gene and cna-derived nucleic acid segments from,, and DNA segments encoding cna from related bacteria. Also disclosed are Col binding protein (CBP) compositions and methods of use. The CBP protein and antigenic epitopes derived therefrom are contemplated for use in the treatment of pathological infections, and in particular, for use in the prevention of bacterial adhesion to Col. DNA segments encoding these proteins and anti-(Col binding protein) antibodies will also be of use in various screening, diagnostic and therapeutic applications including active and passive immunization and methods for the prevention of bacterial colonization in an animal such as a human. These DNA segments and the peptides derived therefrom are contemplated for use in the preparation of vaccines and, also, for use as carrier proteins in vaccine formulations, and in the formulation of compositions for use in the prevention of,infection.


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