The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 11, 2001
Filed:
Feb. 03, 2000
Applicant:
Inventors:
Alan Wellington Faull, Macclesfield, GB;
Andrew John Barker, Macclesfield, GB;
Jason Grant Kettle, Macclesfield, GB;
Assignee:
Zeneca Limited, London, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/1404 ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/1404 ; C07D / ;
Abstract
The invention concerns pharmaceutically useful indoles of formula (I), in which Z, X, T, A, R,, R,, p and q have any of the meanings defined herein, and their pharmaceutically acceptable salts or in vivo hydrolysable esters, as well as pharmaceutical compositions containing them. The novel compounds possess inhibitory activity against monocyte chemoattractant protein-1 (MCP-1). The invention further concerns the use of such indoles in the treatment of a disease or condition mediated by MCP-1.