The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 11, 2001
Filed:
Nov. 16, 1999
Alvin J. Glasky, Tustin, CA (US);
NeoTherapeutics, Inc., Irvine, CA (US);
Abstract
The present invention comprises a method of stimulating regeneration or survival of a mammalian motor neuron or of a mammalian sensory neuron comprising administering to a mammal an effective amount of a compound that is a 9-substituted hypoxanthine derivative linked through a linker to a p-aminobenzoic acid moiety or of a salt or prodrug ester of such a compound. Preferably, the compound is N-4-carboxyphenyl-3-(6-oxohydropurin-9-yl) propanamide. The invention also includes pharmaceutical compositions formulated for stimulation of regeneration of a mammalian motor neuron comprising the 9-substituted hypoxanthine derivative and a pharmaceutically acceptable carrier.