The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 11, 2001
Filed:
Apr. 26, 1999
Applicant:
Inventors:
Paul F. Jackson, Bel Air, MD (US);
Keith M. Maclin, Baltimore, MD (US);
Kevin L. Tays, Elkridge, MD (US);
Barbara S. Slusher, Kingsville, MD (US);
Assignee:
Guilford Pharmaceuticals Inc., Baltimore, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/1683 ; C07F 9/11 ; C07F 9/09 ; A61P 2/100 ; A61P 1/308 ;
U.S. Cl.
CPC ...
A61K 3/1683 ; C07F 9/11 ; C07F 9/09 ; A61P 2/100 ; A61P 1/308 ;
Abstract
The present invention relates to phosphonic acid derivatives that inhibit N-Acetylated &agr;-Linked Acidic Dipeptidase (NAALADase) enzyme activity, pharmaceutical compositions comprising such derivatives, and methods of using such derivatives to inhibit NAALADase activity, to treat a glutamate abnormality and to treat a prostate disease in an animal.