The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 11, 2001

Filed:

Aug. 07, 1998
Applicant:
Inventors:

Pradip Mukerji, Gahanna, OH (US);

Steven A. Lemmel, Columbus, OH (US);

Amanda Eun-Yeong Leonard, Gahannna, OH (US);

Sunita Chaudhary, Pearland, TX (US);

Assignee:

Abbott Laboratories, Abbott Park, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/574 ;
U.S. Cl.
CPC ...
C12N 1/574 ;
Abstract

The subject invention relates to &bgr;-casein expressing constructs which have significant stability when introduced into host cells. These constructs, for purposes of the present invention, have been designated as pRAB-84-69 and pRSB-14. Each construct comprises an isolated DNA sequence comprising i) a nucleotide sequence encoding a protein, wherein said nucleotide sequence is operably linked to a promoter, ii) a nucleotide sequence encoding a first subunit of a kinase, iii) a nucleotide sequence encoding a second subunit of a kinase, iv) a nucleotide encoding a peptidase and v) a nucleotide sequence encoding a bacterial resistance marker. These constructs, once introduced into a host cell, may be used in the production of, for example, recombinant human beta-casein.


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