The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 11, 2001
Filed:
Aug. 18, 1999
Applicant:
Inventors:
James T. Palmer, San Ramon, CA (US);
David Rasnick, San Francisco, CA (US);
Jeffrey Lee Klaus, Redwood City, CA (US);
Assignee:
Axys Pharmaceuticals, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/50 ; C12N 9/99 ; A61K 3/803 ;
U.S. Cl.
CPC ...
C12N 9/50 ; C12N 9/99 ; A61K 3/803 ;
Abstract
Irreversible cysteine protease inhibitors based upon an alkene bond being conjugated to an electron withdrawing group are disclosed. The inhibitor structure also provides a targeting peptide which is specific for different cysteine proteases. The method of making the inhibitors, and methods of using the inhibitors to inhibit cysteine proteases and for therapy are disclosed.