The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 04, 2001
Filed:
Mar. 10, 1998
Applicant:
Inventors:
Richard W. Scott, West Chester, PA (US);
Andrew G. Reaume, West Chester, PA (US);
Karen Dorfman, West Chester, PA (US);
Assignee:
Cephalon, Inc,, West Chester, PA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 ; C12S 1/500 ;
U.S. Cl.
CPC ...
C12N 5/00 ; C12S 1/500 ;
Abstract
This invention discloses a gene-targeted non-human mammal and generational offspring with respect to the gene encoding a mutant protein product of a mutated presenilin 1 gene (PS-1); more specifically, a gene-targeted mouse with respect to the gene sequence encoding the mutant protein product of PS-1 which has been mutated to contain the human P264L mutation. Methods for screening chemical compounds using such mammals are also disclosed.