The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 04, 2001
Filed:
Apr. 08, 1999
Applicant:
Inventors:
Chandran R. Sabanayagam, Allston, MA (US);
Takeshi Sano, Needham, MA (US);
John Misasi, Syracuse, NY (US);
Anson Hatch, Seattle, WA (US);
Charles Cantor, Del Mar, CA (US);
Assignee:
Trustees of Boston University, Boston, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 1/934 ; C12Q 1/68 ; G01N 3/300 ; C07H 2/102 ; C07H 2/104 ;
U.S. Cl.
CPC ...
C12P 1/934 ; C12Q 1/68 ; G01N 3/300 ; C07H 2/102 ; C07H 2/104 ;
Abstract
The present invention generally relates to high density nucleic acid arrays and methods of synthesizing nucleic acid sequences on a solid surface. Specifically, the present invention contemplates the use of stabilized nucleic acid primer sequences immobilized on solid surfaces, and circular nucleic acid sequence templates combined with the use of isothermal rolling circle amplification to thereby increase nucleic acid sequence concentrations in a sample or on an array of nucleic acid sequences.