The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 04, 2001
Filed:
Dec. 22, 1999
Daniel Smolko, Jamul, CA (US);
Ed Sheldon, San Diego, CA (US);
Paul Swanson, Santee, CA (US);
Prashant P. Mehta, Carlsbad, CA (US);
Manuel Jimenez, San Diego, CA (US);
Kenneth A Bloch, S.D., CA (US);
Lorelei Westin, La Mesa, CA (US);
Geoffrey C. Landis, Carlsbad, CA (US);
Nanogen, Inc., San Diego, CA (US);
Abstract
This invention provides an apparatus and method for desalting a low volume solution for use in connection with an electronically addressable microarray. The apparatus comprises a tubular molecular weight cut-off membrane embedded within a ion exchange resin filled chamber. The apparatus provides a very high surface to volume ratio of membrane pore surface to exchange resin capacity for absorbing charged molecules. The design facilitates the speedy removal of charged molecules from test solutions with the resultant desalted solution having a very low ionic strength suitable for use in the electronic transport of nucleic acids, proteins, and cells.