The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 28, 2001
Filed:
Nov. 12, 1999
Applicant:
Inventors:
Susan Cannon-Carlson, Wayne, NJ (US);
Andres Frei, Freehold, NJ (US);
Seoju Lee, Edison, NJ (US);
Roland Mengisen, Freehold, NJ (US);
Marcio Voloch, New York City, NY (US);
David C. Wylie, Cranford, NJ (US);
Assignee:
Schering Corporation, Kenilworth, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 1/00 ; C07K 1/400 ; C07K 1/600 ; C07K 1/700 ; A61K 3/514 ;
U.S. Cl.
CPC ...
C07K 1/00 ; C07K 1/400 ; C07K 1/600 ; C07K 1/700 ; A61K 3/514 ;
Abstract
The present invention provides methods for isolating adjunct isoforms of proteins and converting them to the desired protein. In preferred embodiments, the present invention contemplates the use of acid solutions or zinc solutions to cleave a chemical group from a desired protein. In further preferred embodiments, the present invention contemplates the oxidation of reduced sulfhydryl groups with cleavage of chemical groups to form a functional desired protein.