The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 21, 2001
Filed:
May. 14, 1999
Ira B. Lamster, Wycoff, NJ (US);
The Trustees of Columbia University in the City of New York, New York, NY (US);
Abstract
This invention provides a method of testing for periodontal disease in a subject which comprises detecting an elevated concentration of &bgr;-glucuronidase in saliva from the subject relative to the concentration of &bgr;-glucuronidase present in saliva from a healthy subject. The concentration of &bgr;-glucuronidase in the subject's saliva is determined by adding to a sample of the saliva a substrate for &bgr;-glucuronidase and measuring the amount of a product produced by the action of &bgr;-glucuronidase in the substrate. Also, the concentration of &bgr;-glucuronidase in the subject's saliva is determined by adding to a sample of saliva a labeled antibody specific for &bgr;-glucuronidase and measuring the amount of labeled antibody which forms a complex with &bgr;-glucuronidase present in the saliva.