The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 14, 2001
Filed:
Jun. 26, 1997
Applicant:
Inventors:
Sherin Salaheldin Abdel-Meguid, Exton, PA (US);
Renee Louise Desjarlais, St. Davids, PA (US);
Cheryl Ann Janson, Bryn Mawr, PA (US);
Ward Whitlock Smith, Jr., Bryn Mawr, PA (US);
Baoguang Zhao, King of Prussia, PA (US);
Assignee:
SmithKline Beecham Corporation, Philadelphia, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/48 ; C12N 9/64 ; C12Q 1/37 ; G06F 1/900 ;
U.S. Cl.
CPC ...
C12N 9/48 ; C12N 9/64 ; C12Q 1/37 ; G06F 1/900 ;
Abstract
A novel cathepsin K crystalline stucture is identified. Also disclosed are methods of identifying inhibitors of this protease and methods of inhibiting cathepsin K using inhibitors with certain structural, physical and spatial characteristics.