The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 14, 2001
Filed:
Apr. 12, 1994
Applicant:
Inventors:
Paul James Davis, Beds, GB;
Martine Elisa Verhoeyen, Northants, GB;
Ronald Frank Jacobus De Winter, Bedford, GB;
Assignee:
Unilever Patent Holdings B.V., Rotterdam, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 3/353 ; G01N 3/3566 ; C07K 1/600 ;
U.S. Cl.
CPC ...
G01N 3/353 ; G01N 3/3566 ; C07K 1/600 ;
Abstract
Small specific binding molecules, such as single variable domain antibodies (Dabs) and Fv fragments, can be coupled to solid plastics surfaces or to tracers such as enzymes by means of linkers comprising polypeptides containing from 5 to 20 amino acids and which are hydrophobic and/or contain at least one lysine residue. The coupling can be achieved without significant loss of specific binding activity. The combined Dab/linker or Fv/linker can be prepared by expression in genetically-modified organisms.