The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 07, 2001
Filed:
Jul. 15, 1998
Applicant:
Inventors:
Masabumi Shibuya, Saitama, JP;
Masaji Okamoto, Ibaraki, JP;
Mikio Niwa, Ibaraki, JP;
Tomoe Matsumoto, Ibaraki, JP;
Makoto Asano, Ibaraki, JP;
Tosiaki Segawa, Ibaraki, JP;
Assignee:
Toa Gosei Co., Ltd., Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 2/104 ; C12N 1/500 ;
U.S. Cl.
CPC ...
C07H 2/104 ; C12N 1/500 ;
Abstract
An object of the present invention is to provide a low molecular weight VEGF inhibitor that can be utilized to treat diseases accompanying neovascularization, such as solid tumors. It was found that a polypeptide containing immunoglobulin-like domain 1 and immunoglobulin-like domain 2 but neither immunoglobulin-like main 6 nor immunoglobulin-like domain 7 of the extracellular domain of the VEGF receptor FLT possess VEGF inhibitory activity.