The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 07, 2001
Filed:
May. 15, 1998
Applicant:
Inventors:
David Hugh Jones, Salisbury, GB;
Graham Henry Farrar, Salisbury, GB;
James Christopher Stephen Clegg, Salisbury, GB;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/66 ; A61K 9/52 ; C12N 1/588 ;
U.S. Cl.
CPC ...
A61K 9/66 ; A61K 9/52 ; C12N 1/588 ;
Abstract
A method of making a microparticle that contains DNA coding for a polypeptide is described in which a solvent extraction method is used and solvent extraction takes place at elevated temperature. Oral administration of the microparticle leads to its expression. DNA coding for an immunogen is for stimulating antibody formation in a recipient and DNA coding for a non-immunogenic polypeptide is for gene therapy applications. DNA is incorporated into the microparticle without destruction of its function.