The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 31, 2001
Filed:
Apr. 07, 2000
Scott Howard Dickerson, Chapel Hill, NC (US);
Philip Anthony Harris, Raleigh, NC (US);
Robert Neil Hunter, III, Raleigh, NC (US);
David Kendall Jung, Durham, NC (US);
Karen Elizabeth Lackey, Hillsborough, NC (US);
Robert Walton McNutt, Jr., Durham, NC (US);
Michael Robert Peel, Chapel Hill, NC (US);
James Marvin Veal, Apex, NC (US);
Glaxo Wellcome Inc., Research Triangle Park, NC (US);
Abstract
Compounds of general formula (I) wherein: R,is H or optionally joined with R,to form a fused ring selected from the group consisting of five to ten membered aryl, heteroaryl or heterocyclyl rings, R,and R,are independently H, HET, aryl, C,aliphatic, CN, NO,, halogen, R,, —OR,, —SR,, —S(O)R,, —SO,R,, —NR,R,, —NR,R,, —NR,COR,, —NR,CO,R,, —NR,CONR,R,, —NO,SO,R,, —NR,C(NR,)NHR,, —COR,, —CO,R,, —CONR,R,, —SO,NR,R,, —OCONR,R,, C(NR,)NR,R,, R,and R,are independently halogen, CN, NO,, —CONR,R,, —SO,NR,R,, —NR,R,, or —OR,, where R,and R,are as defined below; R,is OH, NHSO,R,or NHCOCF,; and their use in therapy, especially in the treatment of disorders mediated by cRaf1 kinase.