The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 31, 2001
Filed:
Sep. 07, 2000
Tiziano Bandiera, Gambolò, IT;
Daniele Fancelli, Milan, IT;
Mario Varasi, Milan, IT;
Michele Caruso, Milan, IT;
Jacqueline Lansen, San Vittore Olona, IT;
Antonino Suarato, Milan, IT;
Pharmacia & Upjohn SpA, Milan, IT;
Abstract
A compound of formula (1), wherein R,represents hydrogen, hydroxy, a group of formula OR,, wherein R,is C,-C,alkyl, C,-C,alkenyl; R,represents hydrogen, hydroxy, diethylamino, piperidino, tetrahydropyridino or morpholino, and either R,, taken alone, represtnts hydrogen or hydroxy, and R,and R,, taken alone, independently represent hydrogen, hydroxy or, taken together with the carbon atom, represent a carbonyl group; or R,and R,, taken together, represent a group of formula (A), wherein R,and R,represent a C,-C,alkyl and R,represents hydrogen; R,represents hydrogen or a phenyl group, optionally substituted by methyl, methoxy or halogen and the pharnaceutically acceptable salt thereof, is useful in the treatment of amyloidosis. Processes for the preparation and pharmaceutical compositions are also described.