The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 31, 2001
Filed:
Jan. 12, 2000
Applicant:
Inventors:
Mieke Sibeijn, Av Amersfoort, NL;
Aad Johannes Bouman, Pl Rotterdam, NL;
Robertus Mattheus De Pater, Zl Delft, NL;
Cornelis Frederik Purmer, De Delft, NL;
Assignee:
DSM N.V., Te Heerlen, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 1/706 ; C12P 7/62 ; C07C 6/9732 ; C07C 6/7317 ;
U.S. Cl.
CPC ...
C12P 1/706 ; C12P 7/62 ; C07C 6/9732 ; C07C 6/7317 ;
Abstract
The invention provides a simple and selective method for the deacylation of 4-acylated statins during the preparation of statins from a fermentation broth, more specifically a reduction of impurities from the process, by increasing the pH of the fermentation broth.