The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 31, 2001
Filed:
Dec. 08, 1993
Applicant:
Inventors:
Per Åke Nygren, Enskede, SE;
Hans Wigzell, Hägersten, SE;
Mathias Uhlén, Kvarnbogatan, SE;
Assignee:
Affibody Technology Sweden AB, Stockholm, SE;
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/900 ; C12N 1/562 ;
U.S. Cl.
CPC ...
A61K 3/900 ; C12N 1/562 ;
Abstract
A process for extending the half-life in vivo by a biologically active protein or peptide, characterized by covalently coupling said protein or peptide to a polypeptide fragment capable of binding to a serum protein, whereby when administering the resulting protein or peptide conjugate its binding to the serum protein results in extended biological activity, the use of the protein or peptide conjugate above for manufacturing a medicament which, when administered to a mammal including man, shows extended half-life in vivo; and a method of therapeutic or prophylactic treatment.