The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 24, 2001
Filed:
Mar. 22, 1993
M. Flint Beal, Boston, MA (US);
Kenton J. Swartz, Somerville, MA (US);
Matthew J. During, Rowayton, CT (US);
Andrew Freese, Haverford, PA (US);
The General Hospital Corporation, Boston, MA (US);
Abstract
Neurological diseases such as Huntington's caused by the toxic effects of excetatory amino acids are alleviated by administering metabolic precursors of kynurenic acid to afflicted individuals. These metabolic precursors include kynurenine and tryptophan. Since the amount of kynurenic acid in Huntington's Disease patient's brains is less than that in normal individuals and such decrease is associated with the lesions found in the formation of the lesions. This occurs because kynurenic acid is an inhibitor of excitatory amino acid interactions at their receptors.