The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 24, 2001

Filed:

Dec. 08, 1999
Applicant:
Inventors:

Amy Mae Bunker, Middletown, CT (US);

Xue-Min Cheng, Ann Arbor, MI (US);

Annette Marian Doherty, Paris, FR;

Jeremy John Edmunds, Ypsilanti, MI (US);

Gerald David Kanter, West Bloomfield, MI (US);

Chitase Lee, Ann Arbor, MI (US);

Joseph Thomas Repine, Ann Arbor, MI (US);

Richard William Skeean, Ann Arbor, MI (US);

Assignee:

Warner-Lambert Company, Morris Plains, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; A61K 3/154 ;
U.S. Cl.
CPC ...
C07D / ; C07D / ; A61K 3/154 ;
Abstract

The instant invention is a series of benzothiazine dioxides, or a pharmaceutically acceptable salt thereof, which are potent endothelin A antagonists with profound in vitro activity, and improved syntheses for the Formula 1


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