The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 17, 2001
Filed:
Feb. 01, 1996
Applicant:
Inventors:
David William Fennelly, New York, NY (US);
Francis Michael Sirotnak, New York, NY (US);
Assignee:
Sloan-Kettering Institute of Cancer Research, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/1495 ; A61K 3/150 ; A61K 3/1335 ;
U.S. Cl.
CPC ...
A61K 3/1495 ; A61K 3/150 ; A61K 3/1335 ;
Abstract
This invention provides combination therapy methods, pharmaceutical combinations and compositions for inducing tumor cell regression in cancer patients, particularly metastatic breast cancer patients. The combination methods, combinations and compositions employ both edatrexate and a taxane which are administered simultaneously or sequentially. The combination therapy described here permits the administration of unusually high doses of edatrexate.