The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 17, 2001
Filed:
Jul. 14, 1998
Applicant:
Inventors:
Assignee:
Research Corporation Technologies, Inc., Tucson, AZ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/800 ;
U.S. Cl.
CPC ...
A61K 3/800 ;
Abstract
Peptides containing the amino acid sequence, aa,-aa,-aa,-aa,-(Gly),, devices for implantation coated with the peptides and methods for altering cell adhesion using the peptides are disclosed. The residues aa,, aa,, and aa,are independently Lys, Arg, Orn or, when the residue is N-terminal, Acp. The residue aa,is Ala, Gly, Val, Leu, Ile, Ser, Thr, Cys, Met, Asn, Nle, Nva or Abu. The preferred sequence is KRSR. Peptides containing cell adhesion-related sequences can be incorporated into or coated onto substrates to enhance osteoblast adhesion.